© William Scavone
Title: Ubiquitination and TAP1 Trafficking
Author: William Scavone
Description: Illustrates the ubiquitination/deubiquitination of TAP1, which is integral to the presentation of a viral peptide to an MHC Class 1 molecule in the endoplasmic reticulum, so that the antigen can be expressed on the cell membrane. Pseudomonas eruginosa infection releases Cif into the cell, inhibiting TAP1 deubiquitination which is increasingly degraded, interfering with antigen presentation.
Keywords: Color, Line with Color, Education, Publishing, Web, Allergy / Immunology, Biology, Cell biology / Histology, Disease Management, Molecular Biology