© Cynthia Turner
Title: Cyclooxygenase and NSAIDS
Author: Cynthia Turner
Description: The cyclooxygenase enzyme is shown anchored to the endoplasmic reticulum membrane. Above it, released prostaglandin hormones soar into the cell. Inside it, arachidonic acid is converted into prostaglandins by cyclooxygenase by adding two oxygen molecules. Celecoxib (Celebrex) COX-2 selective NSAID is blocked from the channel of access for COX-1, but gains entry at COX-2 site, and thus inhibits the active site for pain prostaglandin creation.
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